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Table 2 Mean values and standard deviations of parameters that evaluate the contours generated by the three software, before and after the manual correction, for each organ of the prostate patients

From: Systematic evaluation of three different commercial software solutions for automatic segmentation for adaptive therapy in head-and-neck, prostate and pleural cancer

  AA MA VA AM MM VM p value
CTV1
DSC, (SD) 0.86 (0.08) 0.79 (0.05) 0.76 (0.14) 0.88 (0.09) 0.81 (0.04) 0.82 (0.02)  
Sensitivity, (SD) 0.82 (0.11) 0.72 (0.11) 0.70 (0.20) 0.85 (0.11) 0.76 (0.09) 0.82 (0.07)  
IncI, (SD) 0.92 (0.05) 0.89 (0.07) 0.85 (0.06) 0.91 (0.06) 0.88 (0.03) 0.84 (0.07) *
ΔV (%), (SD) −11.48 (7.83) −17.83 (17.60) −17.70 (23.61) −7.73 (6.32) −13.15 (12.11) −1.30 (15.18) °
Δx (mm), (SD) 0.45 (0.33) 0.35 (0.24) 0.38 (0.52) 0.35 (0.24) 0.55 (0.40) 0.85 (0.58)  
Δy (mm), (SD) 0.60 (0.64) 0.93 (0.56) 0.68 (0.56) 1.03 (1.01) 0.83 (0.50) 0.88 (0.90)  
Δz (mm), (SD) 1.25 (1.44) 3.18 (2.39) 1.88 (1.25) 1.28 (1.02) 2.23 (1.19) 2.20 (0.60)  
CTV2
DSC, (SD) 0.77 (0.06) 0.86 (0.01) 0.83 (0.02) 0.87 (0.08) 0.87 (0.01) 0.84 (0.01) * ° =
Sensitivity, (SD) 0.67 (0.12) 0.87 (0.02) 0.84 (0.03) 0.86 (0.09) 0.87 (0.03) 0.85 (0.03) * ° =
IncI, (SD) 0.93 (0.06) 0.85 (0.02) 0.82 (0.04) 0.88 (0.08) 0.86 (0.03) 0.84 (0.02) * #
ΔV (%), (SD) −27.46 (17.74) 2.54 (4.98) 2.78 (8.47) −1.44 (8.11) 1.88 (7.6) 2.12 (6.31) * #
Δx (mm), (SD) 1.63 (1.37) 0.45 (0.41) 0.35 (0.47) 0.98 (1.13) 0.48 (0.41) 0.58 (0.22)  
Δy (mm), (SD) 3.54 (1.28) 2.58 (0.92) 2.55 (1.30) 2.23 (2.62) 2.85 (0.93) 2.68 (1.03)  
Δz (mm), (SD) 1.28 (1.79) 1.28 (1.79) 1.90 (1.62) 1.58 (1.90) 2.23 (1.85) 1.90 (1.63)  
Rectum
DSC, (SD) 0.77 (0.07) 0.75 (0.09) 0.75 (0.04) 0.90 (0.07) 0.87 (0.05) 0.86 (0.05)  
Sensitivity, (SD) 0.88 (0.06) 0.70 (0.17) 0.72 (0.13) 0.92 (0.08) 0.89 (0.05) 0.87 (0.07) * # ^
IncI , (SD) 0.69 (0.11) 0.84 (0.06) 0.79 (0.08) 0.88 (0.07) 0.86 (0.09) 0.86 (0.09)  
ΔV (%), (SD) 30.2 (24.30) −15.38 (24.1) −7.06 (23.65) 4.7 (10.10) 5.2 (13.88) 2.34 (16.64) * °
Δx (mm), (SD) 2.00 (1.78) 2.14 (1.46) 3.36 (1.70) 1.30 (2.11) 0.720 (0.71) 1.92 (1.70)  
Δy (mm), (SD) 2.74 (1.81) 1.36 (0.85) 1.50 (1.71) 1.44 (1.15) 0.90 (0.30) 1.16 (0.76)  
Δz (mm), (SD) 6.54 (5.33) 6.02 (5.25) 6.04 (4.16) 3.78 (4.05) 6.8 (3.71) 7.28 (5.11) ^
Bladder
DSC, (SD) 0.93 (0.03) 0.88 (0.07) 0.72 (0.15) 0.95 (0.04) 0.93 (0.02) 0.93 (0.02) # °
Sensitivity, (SD) 0.93 (0.03) 0.88 (0.12) 0.67 (0.25) 0.96 (0.03) 0.96 (0.03) 0.93 (0.05) =
IncI, (SD) 0.92 (0.06) 0.89 (0.04) 0.89 (0.13) 0.94 (0.04) 0.91 (0.03) 0.93 (0.05) +
ΔV (%), (SD) 1.88 (8.29) −1.70 (14.87) −20.24 (43.21) 2.40 (3.90) 6.12 (5.89) 0.20 (8.79) =
Δx (mm), (SD) 1.10 (0.16) 0.46 (0.46) 0.90 (0.67) 0.66 (0.53) 0.46 (0.46) 0.86 (1.01)  
Δy (mm), (SD) 1.32 (1.53) 3.42 (3.98) 3.44 (4.06) 0.52 (0.56) 0.72 (0.57) 0.76 (0.34)  
Δz (mm), (SD) 1.80 (0.66) 2.02 (1.12) 5.02 (2.92) 2.02 (2.28) 1.80 (1.19) 2.02 (1.43) ^
Bowel
DSC, (SD) 0.83 (0.10) 0.85 (0.09) 0.88 (0.03) 0.89 (0.12) 0.92 (0.02) 0.87 (0.09) =
Sensitivity, (SD) 0.79 (0.15) 0.82 (0.14) 0.88 (0.03) 0.88 (0.18) 0.94 (0.02) 0.84 (0.15) =
IncI, (SD) 0.89 (0.08) 0.90 (0.04) 0.88 (0.05) 0.91 (0.05) 0.91 (0.03) 0.91 (0.01)  
ΔV (%), (SD) −10.78 (17.74) −9.12 (14.13) −0.10 (6.50) −3.38 (18.54) 2.36 (2.98) −7.82 (15.27)  
Δx (mm), (SD) 3.44 (2.63) 2.58 (1.84) 3.32 (3.06) 2.16 (1.79) 2.98 (1.40) 3.46 (3.36)  
Δy (mm), (SD) 8.42 (3.68) 6.88 (3.90) 5.34 (3.72) 4.20 (5.56) 7.48 (3.82) 4.78 (5.87)  
Δz (mm), (SD) 9.78 (10.21) 9.78 (12.15) 6.28 (4.43) 6.02 (11.39) 0.26 (0.58) 5.00 (11.18)  
Femoral head right
DSC, (SD) 0.94 (0.04) 0.94 (0.02) 0.92 (0.03) 0.94 (0.04) 0.94 (0.01) 0.93 (0.02) # ° =
Sensitivity, (SD) 0.94 (0.05) 0.96 (0.02) 0.94 (0.03) 0.94 (0.05) 0.95 (0.02) 0.95 (0.03) °
IncI , (SD) 0.94 (0.04) 0.93 (0.03) 0.90 (0.04) 0.95 (0.04) 0.93 (0.03) 0.91 (0.03) * # ° + ^ =
ΔV (%), (SD) 0.12 (4.98) 2.92 (4.63) 4.82 (4.53) −0.18 (4.92) 2.76 (4.98) 4.22 (5.08) °
Δx (mm), (SD) 0.16 (0.36) 0.36 (0.21) 0.46 (0.49) 0.16 (0.36) 0.36 (0.21) 0.64 (0.31)  
Δy (mm), (SD) 0.18 (0.25) 0.36 (0.38) 0.74 (0.51) 0.26 (0.24) 0.36 (0.38) 0.92 (0.67)  
Δz (mm), (SD) 1.76 (1.11) 1.76 (1.70) 1.76 (2.09) 1.78 (1.43) 2.02 (0.66) 2.04 (1.11)  
Femoral head left
DSC, (SD) 0.94 (0.04) 0.94 (0.03) 0.92 (0.02) 0.94 (0.04) 0.94 (0.02) 0.92 (0.03) * # ^
Sensitivity, (SD) 0.95 (0.04) 0.96 (0.02) 0.94 (0.02) 0.95 (0.04) 0.96 (0.02) 0.95 (0.03) ° =
IncI , (SD) 0.93 (0.05) 0.92 (0.05) 0.90 (0.04) 0.94 (0.05) 0.92 (0.04) 0.90 (0.05) # ^
ΔV (%), (SD) 2.30 (5.73) 4.92 (6.06) 5.42 (6.47) 1.24 (6.01) 4.94 (5.70) 4.94 (7.35) * # + ^
Δx (mm), (SD) 0.62 (0.91) 0.68 (0.67) 0.66 (0.49) 0.62 (0.91) 0.68 (0.67) 0.76 (0.44)  
Δy (mm), (SD) 0.16 (0.36) 0.36 (0.38) 0.64 (0.31) 0.16 (0.36) 0.36 (0.38) 0.76 (0.51)  
Δz (mm), (SD) 3.28 (1.91) 2.26 (1.85) 2.02 (1.92) 2.02 (1.43) 1.52 (1.04) 2.30 (1.37)  
  1. For automatic segmentation: *AA vs. MA: p<0.043, #AA vs. VA: p<0.043, °MA vs. VA: p<0.043.
  2. For automatic segmentation+ manual correction: +AM vs. MM: p<0.043, ^AM vs. VM: p<0.043, =MM vs. VM: p<0.043.
  3. Abbreviations: CTV = Clinical target volume; SD = Standard deviation, DSC = DICE similarity coefficient, IncI = inclusiveness index, AA = Abas Automatic, MA = MiM Automatic, VA = Velocity Automatic, AM = Abas Manual Correction, MM = MiM Manual Correction, VM = Velocity Manual Correction.
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Radiation Oncology

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