Figure 1From: Preclinical evaluation of sunitinib, a multi-tyrosine kinase inhibitor, as a radiosensitizer for human prostate cancerExpression of RTK’s detected by western blot analysis. Three prostate cell lines PC3, LNCaPs and DU145 were assessed for the presence of RTKs, shown to be targets of sunitinib (c-KIT, VEGFR-2, PDGFR- and FLT3). DU145 was found to be positive for all except for FLT3. PDGFR- was the only RTK found to be expressed in PC3 cells while LNCaPs were found to be negative for all four.Back to article page