Table 3 Univariate analysis of predictive factors for overall and progression-free survival

Characteristic

HR (95% CI)

P value

HR (95% CI)

P Value

Age, years

≥ 74

1

< 74

1.87 (0.93–3.78)

0.080

1.42 (0.83–2.44)

0.196

Sex

Male

1

Female

0.93 (0.48–1.82)

0.875

0.86 (0.51–1.47)

0.588

COPD stage

0–II

1

III–IV

0.75 (0.37-1.54)

0.413

0.66 (0.37-1.17)

0.594

History of other type of cancer

Yes

1

No

1.55 (0.78–3.09)

0.211

1.29 (0.74–2.24)

0.374

ECOG performance status

0–1

1

2–3

2.03 (1.04–3.95)

0.037

1.68 (0.99–2.85)

0.050

Lung cancer stage

IA (T1)

1

IB (T2)

1.28 (0.53–3.08)

0.586

1.11 (0.54–2.27)

0.776

Lung cancer histology

Non-squamous

1

Squamous

1.16 (1.01–1.34)

0.043

1.09 (0.97–1.22)

0.173

Staging PET SUV_max

< 6.2

1

≥ 6.2

2.10 (1.01-4.33)

0.028

1.81 (1.05–3.10)

0.032

Gross tumor volume, cm³

< 9.6

1

≥ 9.6

1.55 (0.79–3.05)

0.204

1.42 (0.84–2.42)

0.195

Disease status

Medically inoperable

1

Operable

0.36 (0.14–0.94)

0.036

0.51 (0.26–1.02)

0.055

Tumor location

Peripheral

1

Central

0.97 (0.34–2.76)

0.954

0.89 (0.35–2.25)

0.809

Radiation pneumonitis

No

1

Yes

1.19 (0.65–2.16)

0.571

0.92 (0.43–1.94)

0.819