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Table 1 Examples of new low- and high-molecular-weight boron delivery agents currently under evaluation*

From: Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer

Boronated unnatural amino acids[1214]

Carboranyl nucleosides[16, 17]

Dodecaborate cluster lipids and cholesterol derivatives [18]

Boronated porphyrins [1921]

Boron containing immunoliposomes [22] and liposomes [2326]

Boronated EGF and anti-EGFR and VEGFR MoAbs [2733]

Boronated DNA intercalators [34]

Boron-containing nanoparticles [35, 36]

Transferrin–polyethylene glycol (TF–PEG) liposomes [37, 38]

Carboranyl porphyrazines [39]

Dodecahyrdo-closo-dodecaborate clusters [18]

Boronated cyclic peptides [15]

 

Boron nitride nanotubes [40]

  1. * The numbers indicated in brackets are cited in the reference section.