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Table 5 Mean bother scores before treatment and differences after treatment relative to baseline scores (quartiles in brackets; negative differences indicate a quality of life improvement; bold numbers indicate significant difference between treatment groups)

From: Dose-escalation using intensity-modulated radiotherapy for prostate cancer - evaluation of quality of life with and without 18F-choline PET-CT detected simultaneous integrated boost

  

time A

0.5 SD

time A-time B

time A-time C

time A-time D

significant differences

       

A vs. B

A vs. C

A vs. D

urinary bother score

GTVPET < 4 cc

81

(75;84;92)

7

17

(-5;23;32)

0

(-11;-4;11)

1

(-11;-4;7)

+

-

-

 

GTVPET ≥4 cc

83

(75;86;98)

8

15

(0;7;34)

5

(-9;0;14)

-2

(-9;0;4)

+

-

-

urinary bother score

distance GTVPET to bladder ≥1 cm

81

(75;86;90)

6

13

(2;14;37)

0

(-4;4;20)

-3

(-11;0;0)

+

-

-

 

distance GTVPET to bladder < 1 cm

81

(75;82;96)

9

21

(0;21;37)

8

(-4;0;21)

4

(-7;0;11)

+

+

-

bowel bother score

GTVPET < 4 cc

89

(86;94;100)

8

10

(-4;14;27)

-1

(-7;0;4)

-1

(-7;0;4)

+

-

-

 

GTVPET ≥4 cc

95

(89;100;100)

5

15

(1;12;21)

9

(0;2;14)

3

(0;0;4)

+

+

-

bowel bother score

distance GTVPET to rectum ≥3 mm

91

(89;96;100)

7

11

(0;12;19)

2

(-6;0;4)

-1

(0;0;4)

+

-

-

 

distance GTVPET to rectum < 3 mm

91

(88;98;100)

7

14

(-6;14;27)

7

(0;4;11)

2

(0;0;5)

+

+

-

  1. Abbreviations: SD = standard deviation of baseline value