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Table 5 Mean bother scores before treatment and differences after treatment relative to baseline scores (quartiles in brackets; negative differences indicate a quality of life improvement; bold numbers indicate significant difference between treatment groups)

From: Dose-escalation using intensity-modulated radiotherapy for prostate cancer - evaluation of quality of life with and without 18F-choline PET-CT detected simultaneous integrated boost

   time A 0.5 SD time A-time B time A-time C time A-time D significant differences
        A vs. B A vs. C A vs. D
urinary bother score GTVPET < 4 cc 81
(75;84;92)
7 17
(-5;23;32)
0
(-11;-4;11)
1
(-11;-4;7)
+ - -
  GTVPET ≥4 cc 83
(75;86;98)
8 15
(0;7;34)
5
(-9;0;14)
-2
(-9;0;4)
+ - -
urinary bother score distance GTVPET to bladder ≥1 cm 81
(75;86;90)
6 13
(2;14;37)
0
(-4;4;20)
-3
(-11;0;0)
+ - -
  distance GTVPET to bladder < 1 cm 81
(75;82;96)
9 21
(0;21;37)
8
(-4;0;21)
4
(-7;0;11)
+ + -
bowel bother score GTVPET < 4 cc 89
(86;94;100)
8 10
(-4;14;27)
-1
(-7;0;4)
-1
(-7;0;4)
+ - -
  GTVPET ≥4 cc 95
(89;100;100)
5 15
(1;12;21)
9
(0;2;14)
3
(0;0;4)
+ + -
bowel bother score distance GTVPET to rectum ≥3 mm 91
(89;96;100)
7 11
(0;12;19)
2
(-6;0;4)
-1
(0;0;4)
+ - -
  distance GTVPET to rectum < 3 mm 91
(88;98;100)
7 14
(-6;14;27)
7
(0;4;11)
2
(0;0;5)
+ + -
  1. Abbreviations: SD = standard deviation of baseline value