Skip to main content

Table 6 SBRT of adrenal gland metastases

From: Stereotactic body radiation therapy for abdominal oligometastases: a biological and clinical review

  Patients (N) Median dose (Gy) Median follow up (mos) Outcomes
Chawla et al., 2009 [62] 30 40 Gy (16–50)/4–10 fractions 9.8 At 1-year: survival: 44%, LC: 55%, distant control rate, 13%
     No late Grade ≥2 toxicity
Holy et al., 2011[63] 18 20-40 Gy/5 fractions 21 In 13 patients with isolated adrenal metastasis: LC :77%, OS:23 months
Casamassima et al., 2012 [64] 48 36 Gy/3 fractionsa 16.2 At 1 and 2 years, LC: 90%; OS: 39.7% and 14.5%, resp.
     1 case of Grade 2 adrenal insufficiency
Scorsetti et al., 2012 [65] 34 32 Gy/4 fractions 41 At 1 and 2 years: LC 66% and 32%, resp.
     No significant acute and late toxicities
  1. a70% isodose, 17.14 Gy per fraction at the isocenter. Eight patients were treated with single-fraction (23 Gy) stereotactic radiosurgery.