Table 6 SBRT of adrenal gland metastases
From: Stereotactic body radiation therapy for abdominal oligometastases: a biological and clinical review
Patients (N) | Median dose (Gy) | Median follow up (mos) | Outcomes | |
|---|---|---|---|---|
Chawla et al., 2009 [62] | 30 | 40 Gy (16–50)/4–10 fractions | 9.8 | At 1-year: survival: 44%, LC: 55%, distant control rate, 13% |
No late Grade ≥2 toxicity | ||||
Holy et al., 2011[63] | 18 | 20-40 Gy/5 fractions | 21 | In 13 patients with isolated adrenal metastasis: LC :77%, OS:23 months |
Casamassima et al., 2012 [64] | 48 | 36 Gy/3 fractionsa | 16.2 | At 1 and 2 years, LC: 90%; OS: 39.7% and 14.5%, resp. |
1 case of Grade 2 adrenal insufficiency | ||||
Scorsetti et al., 2012 [65] | 34 | 32 Gy/4 fractions | 41 | At 1 and 2 years: LC 66% and 32%, resp. |
No significant acute and late toxicities |