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Table 4 SBRT of liver oligometastases

From: Stereotactic body radiation therapy for abdominal oligometastases: a biological and clinical review

 

Liver metastases (N)

Dose (Gy × fr)

Median follow up (mos)

Actuarial LC rate (%)

    

at 12 mos

at 24 mos

Herfarth et al. 2001 [40]

56

14-26 × 1

6

75

 

Wulf et al. 2001 [41]

23

30 × 3

9

76

61

Wulf et al. 2006 [42].

51

variable dose × (1–3)

15

92

66

Hoyer et al. 2006 [43]

97/141*lesions

45 × 3

4.3 years

 

79

Méndez-Romero et al. 2006 [44]

34

37.5 × 3

13

100

86

Kavanagh et al. 2006 [45].

36

60 × 3

19

93 (at 18 mos)

 

Milano et al. 2008 [46].

120/293*lesions

50 × 5

41

 

67

Rusthoven et al. 2009 [47].

63

36 - 60 × 3

16

95

92

Van der Pool et al. 2010 [48]

31

37.5 - 45 × 3

26

100

74

Rule et al. 2010 [49].

37

30 × 3

20

 

56

  

50 × 5

  

89

  

60 × 5

  

100

  1. LC: local control.
  2. * Ratio of liver oligometastases to total number of oligometastases.