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Table 4 Overview of literature

From: Total skin electron beam therapy as palliative treatment for cutaneous manifestations of advanced, therapy-refractory cutaneous lymphoma and leukemia

Author

Stage

Type of radiation treatment

Total dose

Treatment response

PFS

OS

Lindahl et al.[16]

T1 5.7%

TSEBT

High-dose (30 Gy) n = 25

High-dose: CR 68%

9 months median

n. a.

 

T2 40%

 

Low-dose (4 Gy) n = 10

Low-dose:CR 10%

  
 

T3 48.6%

     
 

T4 5.7%

     

Navi et al.[17]

T2 57%

TSEBT (+/- HN2)

36 Gy (range 30-40 Gy)

T2: CCR 75%

T2: 8.5 years

T2: 10.9 years

 

T3 43%

  

T3: CCR 47%

T3: 2.9 years

T3: 4.7 years

Kamstrup et al.[16]

T2 n = 6

TSEBT

10 Gy

OR 90%

median response duration 5.2 months

n. a.

 

T3 n = 2

  

CR 30%

  
 

T4 n = 2

     

Chinn et al.[18]

T2 n = 55

TSEBT (+/- HN2)

Mostly 36 Gy

T2: CR 76%

Freedom from recurrence at 1 year 41%

T2: 10.7 years

 

T3 n = 27

  

T3: CR 44%

 

T3: 3.6 years

This Analysis

IIB n = 4

TSEBT

Median 29 Gy

OR 92%

5 months

10 months

 

III n = 1

  

CCR 52%

  
 

IVA n = 10

     
 

IVB n = 7

     
  1. Abbreviations: TSEBT total skin electron beam therapy, CR complete remission, CCR clinical complete remission, OR overall response, PFS progression free survival, OS overall survival.