Table 3 Factors may or may not affect the patterns of failure in patients with glioblastoma or anaplastic astrocytoma
Patients with glioblastoma | |||||||||
|---|---|---|---|---|---|---|---|---|---|
MIB-1 (n =58) | Extent of surgical removal (n =58) | Chemotherapy (n =53) | |||||||
Sites of | < 30 | ≧ 30 | P value | > 80% | < 80% | P value | ACNU | TMZ | P value |
recurrence | based | based | |||||||
n = 30 | n = 28 | n = 20 | n = 38 | n = 23 | n = 30 | ||||
Central | 25 | 15 | 0.014 | 15 | 25 | 0.47 | 17 | 20 | 0.57 |
Others * | 5 | 13 | 5 | 13 | 6 | 10 | |||
Patients with anaplastic astrocytoma | |||||||||
MIB-1 (n =16) | Extent of surgical removal (n =16) | Chemotherapy (n =13) | |||||||
Sites of | < 30 | ≧ 30 | P value | > 80% | < 80% | P value | ACNU | TMZ | P value |
recurrence | |||||||||
based | based | ||||||||
n = 13 | n = 3 | n = 5 | n = 11 | n = 5 | n = 8 | ||||
Central | 9 | 2 | 0.93 | 3 | 8 | 0.61 | 4 | 6 | 0.84 |
Others * | 4 | 1 | 2 | 3 | 1 | 2 | |||