Table 1 Patient characteristics and treatments (n = 131)
Characteristics | Anaplastic astrocytoma | Glioblastoma | |
|---|---|---|---|
n = 26 (%) | n = 105 (%) | ||
Age | Â | Â | Â |
|  | Median | 52.5 years | 59 years |
|  | (range) | (18–75 years) | (16–77 years) |
Sex | Â | Â | Â |
| Â | Male | 14 (54) | 59 (56) |
| Â | Female | 12 (46) | 46 (44) |
Original tumor location | Â | Â | |
| Â | Frontal lobe | 11 (42) | 36 (34) |
| Â | Temporal lobe | 5 (19) | 35 (33) |
| Â | Parietal lobe | 3 (12) | 20 (19) |
| Â | Thalamus | 4 (15) | 3 (3) |
| Â | Occipital | 1 (4) | 6 (6) |
| Â | Cerebellum | 2 (8) | 2 (2) |
| Â | Basal ganglia | 0 (0) | 2 (2) |
| Â | Brainstem | 0 (0) | 1 (1) |
MIB-1 labeling index | Â | Â | |
|  | Median (range) | 18.2% (2–35) | 29.8% (2–80) |
Radiotherapy | Â | Â | |
|  | Median dose | 60 Gy | 60 Gy |
|  | (range) | (54–68.4 Gy) | (54–71.2 Gy) |
Extent of surgical removal | Â | Â | |
| Â | Gross total removal | 3 (12) | 18 (17) |
| Â | Subtotal removal | 5 (19) | 15 (14) |
| Â | Partial removal | 11 (42) | 59 (56) |
| Â | Biopsy only | 7 (27) | 13 (12) |
Chemotherapy | Â | Â | |
| Â | ACNU (Nimustine) | 11 (42) | 44 (42) |
| Â | Temozolomide | 11 (42) | 45 (43) |
| Â | None | 4 (15) | 14 (13) |
| Â | Unknown | 0 (0) | 2 (2) |