Figure 6
From: Mechanisms of increased risk of tumorigenesis in Atm and Brca1 double heterozygosity
Induction of micronuclei in MEF cells exposed to 2 Gy of photons. Individual cells were visualized with Acridine Orange staining and micronuclei (MN) per binucleated cell (BN) were score under fluorescence microscope. More than 500 BN cells were counted for each sample. Data were pooled from three independent experiments. * indicates the significant difference (p < 0.05) compared with ATMwt/BRCA1wt cells exposed to the same dose of photons.