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Table 1 Characteristics of 112 high-grade, Stage II and III soft-tissue sarcoma cases

From: Neoadjuvant chemoradiation compared to neoadjuvant radiation alone and surgery alone for Stage II and III soft tissue sarcoma of the extremities

CHARACTERISTIC

NCR

NR

SA

P

All

39

37

36

 

Sex/

    

   Male

19

22

23

0.39

   Female

20

15

13

 

Grade*

    

   2

3

5

8

0.08

   3

17

7

10

 

   4

16

21

13

 

Age (years)

    

   Median (range)

58 (17-88)

71 (32-93)

54.5 (18-86)

0.03

Anatomic site

    

   Upper extremity

8

7

9

0.81

   Lower extremity

31

30

27

 

Histology

    

   Leiomyosarcoma

3

3

4

 

   Liposarcoma

4

10

4

 

   MFH

4

9

10

0.09

   Myxofibrosarcoma

12

8

2

 

   Sarcoma NOS

5

2

1

 

   Other

11a

5b

15c

 

Tumor size (cm)d

    

   Median (range)

10.6 (0.9-29.6)

8 (2.7-25)

4 (0.4-25)

0.01

   <5 cm

4

9

19

0.0002

   5-10 cm

14

13

6

 

   >10 cm

20

11

6

 

Primary disease

37

31

23

0.002

Relapsed disease

2

6

13

 
  1. NCR, neoadjuvant chemoradiation; NR, neoadjuvant radiation alone; SA, surgery alone; MFH, malignant fibrous histiocytoma; NOS, not otherwise specified; cm, centimeters.
  2. *: Grade data missing on 3 NCR, 4 NR and 5 SA-treated patients.
  3. a: synovial sarcoma (n = 5); epithelioid sarcoma (n = 2); myxoid liposarcoma (n = 1); malignant peripheral nerve sheath tumor (n = 1); extraskeletal myxoid chondrosarcoma (n = 1); sclerosing epithelioid fibrosarcoma (n = 1).
  4. b: synovial sarcoma (n = 1); myxoid liposarcoma (n = 2); malignant peripheral nerve sheath tumor (n = 1); clear cell sarcoma of soft tissue (n = 1).
  5. c: synovial sarcoma (n = 4); epithelioid hemangiosarcoma (n = 1); epithelioid sarcoma (n = 1); myxoid liposarcoma (n = 1); malignant peripheral nerve sheath tumor (n = 2); mixed histologies (n = 1); clear cell sarcoma of soft tissue (n = 2); adult fibrosarcoma (n = 1); mesenchymal chondrosarcoma (n = 1); angiosarcoma (n = 1).
  6. d: Does not total 112 due to missing tumor size data for 10 patients.