Skip to main content

Table 5 Pearson's correlation coefficients of immune cells proportions with dosimetric parameters

From: The evolution of rectal and urinary toxicity and immune response in prostate cancer patients treated with two three-dimensional conformal radiotherapy techniques

14th date of 3D CRT 15-20 days after completion of 3D CRT
Variable vs. Variable Pearson's correlation p Variable vs. Variable Pearson's correlation p
T cells
(CD3+CD56-)
Dmin -0.5869 (20)* 0.012 NK cells
(CD3-CD56low)
Percentage of rectum receiving 70 Gy -0.5436 (23) 0.024
  Dmean -0.5068 (27) 0.032     
  Dmax of rectum -0.4918 (29) 0.038     
  Dmax of urinary bladder -0.6089 (18) 0.007     
  Percentage of urinary bladder receiving 70 Gy -0.4906 (29) 0.007     
NKT cells
(CD3+CD56+)
Dmin of rectum -0.5776 (20) 0.012 NKT cells
(CD3+CD56+)
Dmax of rectum -0.6755 (14) 0.000
  Dmean of rectum -0.7243 (12) 0.001   Percentage of rectum receiving 70 Gy -0.4148 (42) 0.031
  Percentage of rectum receiving 40 Gy -0.7363 (11) 0.000   Dmax of urinary bladder -0.6210 (17) 0.001
  Percentage of rectum receiving 50 Gy -0.5613 (22) 0.015     
NK cells
(CD3-D56low)
Dmin of rectum 0.3963 (47) 0.033 Activated B cells (CD19+CD20+
CD38+)
Dmin of rectum 0.4582 (34) 0.016
  Dmean of rectum 0.3724 (53) 0.047   Dmean of rectum 0.4342 (38) 0.024
  Percentage of urinary bladder receiving 70 Gy 0.5152 (26) 0.004   Percentage of rectum receiving 50 Gy 0.4011 (46) 0.038
      Percentage of rectum receiving 60 Gy 0.5800 (20) 0.002
Terminally differentiated NK cells
(CD3-CD56+)
Dmin 0.4887 (30) 0.040 Terminally differentiated
NK cells
(CD3-CD56+)
Dmax of rectum -0.5549 (22) 0.000
  Percentage of rectum receiving 70 Gy 0.4835 (30) 0.042   Dmax of urinary bladder -0.4608 (34) 0.016
  Percentage of urinary bladder receiving 70 Gy 0.5226 (26) 0.026     
  GI, GU toxicity 0.5166 (26) 0.028     
  1. *Required sample size for correlation coefficient for α = 0.05 and power of the test β = 0.80 is given in the brackets