Skip to main content

Table 3 Univariate analysis of local tumor control and overall survival (log rank of Kaplan-Meier method)

From: Clinical Analysis of stereotactic body radiation therapy using extracranial gamma knife for patients with mainly bulky inoperable early stage non-small cell lung carcinoma

Characteristic

Patients, No.

Local

control

Overall survival

   

Χ 2

P

Χ 2

P

Gender

Male

32

1.054

0.305

2.671

0.102

 

Female

11

    

Age

≤70

23

0.832

0.362

0.116

0.733

 

>70

20

    

Karnofsky performance status

70

7

1.584

0.453

1.769

0.413

 

80

19

    
 

90

17

    

Comorbidities

Yes

33

0.442

0.506

0.007

0.932

 

No

10

    

Type

Central

8

0.427

0.514

0.173

0.678

 

Periphery

35

    

Histology

Squamous cell carcinoma

17

0.696

0.874

0.975

0.807

 

Adenocarcinoma

14

    
 

Adenosquamouscarcinoma

1

    
 

Unspecified

11

    

Clinical stage

I

23

14.888

0.000

7.926

0.005

 

II

20

    

Tumor size

≤3 cm

4

12.824

0.005*

5.361

0.147

 

3-5 cm

20

    
 

5-7 cm

10

    
 

>7 cm

9

    

Dose/fraction

(50% isodose line)

<6Gy

27

1.337

0.248

0.979

0.322

 

≥6Gy

16

    

BED (50% isodose line)

<60Gy

17

0.550

0.458

0.033

0.856

 

≥60Gy

26

    

Chemotherapy

no

30

2.194

0.139

6.000

0.014

 

yes

13

    
  1. Abbreviation: BED: biological effective dose.
  2. *: pairwise comparisons of local control of different size tumors.