Figure 4

Neutron capture radiographic image in murine liver sections after administration of BSH or CG-HVJ-E-BSH. Liver sections from tumor-bearing mice were prepared and frozen 1 hour after BSH (35 μg boron/g) injection or 24 hours after CG-HVJ-E-BSH (1.2 μg boron/g) injection. The sections were placed on CR-39 detector plates and exposed to thermal neutrons (2.1 × 10¹³ neutrons/m²·s¹) for 1 hour. A) The number of α particles per 10,000 μm² section was counted by VH Analyzer software after NaOH etching. B) The number of α particles per 10,000 μm² section of BSH or C) of CG-HVJ-E-BSH (n = 3). D) Tumor-to-normal liver tissue (T/N) ratio for the number of α particles