Intraoperative radiation therapy for advanced cervical metastasis: a single institution experience

Radiation Oncology

Table 3 Statistical correlation of disease characteristics with survival outcomes

Characteristic (%)	Median OS (y)	p	Median RFS (y)	p
IORT dose		0.863		0.029
≤ 1500 cGy (39.1%)	1.2		1.5
> 1500 cGy (60.9%)	1.5		NE
Energy		0.064		0.006
4 MeV (29%)	1.0		NE
5 MeV (51%)	1.6		NE
6+ MeV (20%)	1.0		0.8
ECE		0.569		0.310
Yes (12%)	1.4		0.9
No (88%)	1.7		3.9
LVI/AVI		0.071		0.064
Yes (16%)	0.8		0.7
No (84%)	1.7		3.9
PNI		< 0.001		0.387
Yes (17%)	0.6		1.1
No (83%)	1.9		3.9
Dermal Invasion		0.035		0.911
Yes (21%)	0.9		NE
No (79%)	1.9		3.1
Carotid Involvement		0.010		0.199
Yes (33%)	1.0		1.1
No (67%)	2.2		NE
Vasc. Complications		0.823		0.894
Yes (11%)	1.2		1.1
No (89%)	1.2		1.5
Prior RT		0.263		0.246
Yes (81%)	1.4		3.2
No (19%)	2.2		NE
Previous Chemo		0.419		0.045
Yes (51%)	1.6		1.2
No (49%)	0.9		10.4
Post Surgery RT		0.457		0.127
No (76%)	1.5		10.4
Yes (24%)	1.6		1.2

Survival times estimated using Kaplan-Meier method and tested between groups using the long-rank test.
NE - not estimable

ISSN: 1748-717X