Table 4 Modelled breast cancer risk for different α/β-values for mantle field treatment of Hodgkin's disease and comparison with published data.
From: Dose-response relationship for breast cancer induction at radiotherapy dose
EAR [/10000 PY] | Dores et al[16] | Hancock and Hoppe[14] | Swerdlow et al[15] | van Leeuwen[17] | average |
|---|---|---|---|---|---|
observed | 10.5 | 21.5 | 3.1 | 29.4 | 16.1 |
α/β = 1 Gy | 12.0 (10.9-13.7) | 13.2 (12.0-15.0) | 12.4 (9.1-15.1) | 14.5 (13.2-16.6) | 13.0 |
α/β = 3 Gy | 10.7 (8.3-14.3) | 11.8 (9.2 -15.8) | 11.1 (8.7-14.9) | 13.0 (10.1-17.4) | 11.7 |
α/β = 5 Gy | 10.3 (8.0-13.7) | 11.3 (8.1-13.7) | 10.7 (8.4-14.2) | 12.5 (9.8-16.6) | 11.2 |