Table 1 Dosimetric comparison of IMRT with 3DCRT: median value (range)

PTV

D_mean (Gy)

46.6 (46.4 - 46.9)

46.0 (45.6 - 47.0)*

46.6 (46.3 - 48.3)

1547 cm³

V_45Gy

99.5% (98.7% - 99.8%)

87.2% (80.0% - 93.4%)†

98.4% (97.7% - 99.6%)*

(1459 -

D_99% (Gy)

45.3 (44.8 - 45.8)

35.2 (10.7 - 40.3)†

44.9 (44.2 - 45.2)*

1968 cm³)

D_1% (Gy)

47.6 (47.2 - 47.9)

48.3 (47.7 - 50.5)†

47.5 (47.1 - 48.2)

HI

3.2% (2.5% - 3.6%)

N/A

4.2% (3.0% - 5.3%)†

CI

1.16 (1.09 - 1.23)

N/A

1.35 (1.27 - 1.38)†

Bladder

D_mean (Gy)

38.6 (31.1 - 42.4)

37.9 (27.5 - 44.2)

41.8 (31.0 - 45.0)†

72 cm³

V_30Gy

74.7% (40.8% - 90.0%)

72.6% (36.7% -96.6%)

85.8% (47.2% - 100%)†

(32-652 cm³)

V_40Gy

56.8% (26.2% - 76.6%)

58.5% (27.6% - 84.0%)

75.4% (38.0% - 100%)†

Femoral heads

D_mean (Gy)

27.1 (20.8 - 29.6)

24.9 (22.4 - 30.7)

28.5 (21.9 - 31.8)*

211 cm³

V_30Gy

28.0% (17.8% - 44.2%)

22.6% (12.0% - 33.3%)

31.9% (13.2% - 57.4%)

(151-393 cm³)

V_40Gy

3.4% (1.1% - 7.0%)

6.3% (1.9% - 13.2%)*

9.1% (3.5% - 14.6%)†

Pelvic bones

D_mean (Gy)

34.2 (30.5 - 36.2)

34.7 (31.9 - 36.8)*

36.7 (32.3 - 38.4)†

914 cm³

V_30Gy

69.8% (55.6% - 76.3%)

66.7% (61.8% - 72.3%)

74.9% (63.4% - 81.0%)

(725-1338 cm³)

V_40Gy

47.0% (35.2% - 52.8%)

53.9% (46.5% - 59.2%)†

56.9% (41.3% - 63.6%)†

Sigmoid/Colon

D_mean (Gy)

18.9 (10.4 - 27.9)

17.5 (9.8 - 23.6)

25.5 (13.7 - 31.1)†

outside PTV

V_20Gy

41.6% (13.2% - 72.6%)

38.0% (11.5% - 54.0%)

60.6% (24.9% - 75.2%)†

162 cm³

V_30Gy

17.6% (5.1% - 48.1%)

10.4% (3.0% - 36.9%)

36.9% (10.8% - 63.2%)†

(23 - 389 cm³)

V_40Gy

4.0% (0.7% - 19.2%)

2.4% (0.4% - 30.3%)

18.3% (5.1% - 38.5%)†

Small bowel

D_mean (Gy)

18.6 (11.2 - 34.0)

21.0 (8.6 - 34.2)

25.2 (15.9 - 40.0)†

251 cm³

V_5Gy (cc)

224 (2.5 - 526)

225 (2.2 - 525)

234 (2.5 - 530)

(3 - 537 cm³)

V_15Gy (cc)

138 (0.1 - 257)

144 (0.4 - 413)*

157 (2.2 - 428)†

V_25Gy (cc)

81 (0.0 - 142)

79 (0.0 - 149)

123 (0.5 - 183)†

V_40Gy (cc)

45 (0.0 - 111)

50 (0.0 - 118)

76 (0.0 - 156)†

V_45Gy (cc)

37 (0.0 - 100)

33 (0.0 - 74)

53 (0.0 - 121)†

Normal tissues

D_mean (Gy)

19.5 (12.0 - 21.6)

17.5 (12.8 - 20.6)*

20.5 (17.4 - 22.4)†

10.3*10³ cm³

V_10Gy

69.5% (58.0% - 76.9%)

64.9% (53.3% - 75.6%)*

73.8% (62.2% - 80.7%)†

(7.7*10³ -

V_20Gy

48.3% (39.5% - 52.7%)

42.0% (32.6% - 52.7%)*

50.5% (40.0% - 58.3%)*

   18.9*10³ cm³)

V_30Gy

20.3% (16.5% - 27.4%)

17.3% (12.6% - 20.2%)*

23.5% (16.8% - 27.8%)

V_40Gy

6.7% (4.0% - 9.2%)

8.3% (4.2% - 10.9%)*

11.0% (6.7% - 15.7%)†

V_45Gy

2.3% (1.2% - 5.1%)

4.4% (2.1% - 6.0%)†

5.2% (2.8% - 6.4%)†