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Figure 4 | Radiation Oncology

Figure 4

From: Biological in-vivo measurement of dose distribution in patients' lymphocytes by gamma-H2AX immunofluorescence staining: 3D conformal- vs. step-and-shoot IMRT of the prostate gland

Figure 4

Dose-lymphocyte-histogram (DLH). In this integral histogram, data of 20 patients per group (3D and SSIMRT) are summarized in two curves. Standard errors are shown. The dose initially was correlated with each number of γH2AX foci. Background foci levels were subtracted. Referring to a previously generated calibration line (Figure 2), the count of γH2AX foci leads to the equivalent delivered dose for each lymphocyte. Each point contains the mean relative sum of lymphocytes with at least the shown relative dose (≥ x). 100% dose is equivalent to 2 Gy for 3D and 2.17 Gy for SSIMRT. This causes the slight shift between the points of the curves.

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Radiation Oncology

ISSN: 1748-717X

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