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Table 3 Apoptosis data obtained after the irradiation of PBL at 1, 2 and 8 Gy

From: Combined low initial DNA damage and high radiation-induced apoptosis confers clinical resistance to long-term toxicity in breast cancer patients treated with high-dose radiotherapy

 

Mean ± SD

Median (range)

Tertiles

P

DSB/Gy/DNA unit

1.70 ± 0.83

1.46 (0.63-4.08)

1.28-1.78

0.290

RIA 1Gy

13.33 ± 7.26

12.36 (2.51-29.00)

9.58-15.52

0.971

RIA 2Gy

18.20 ± 7.82

17.79 (4.17-32.08)

14.40-22.43

0.996

RIA 8Gy

29.70 ± 10.05

30.44 (9.02-44.10)

24.83-34.40

0.977

α

13.08 ± 7.21

12.64 (1.64-26.63)

9.91-15.63

0.994

β

7.93 ± 2.68

7.85 (3.18-12.57)

7.14-9.29

0.943

  1. Abbreviations: DSB/Gy/DNA unit = double-strand breaks induced per Gy and per 200 Mbp; RIA = radiation-induced apoptosis at 1, 2 and 8 Gy after 24 hours. α and β are the constants that define the model. P values were obtained after a Kolmogorov-Smirnov test.