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Figure 4 | Radiation Oncology

Figure 4

From: The use of caspase inhibitors in pulsed-field gel electrophoresis may improve the estimation of radiation-induced DNA repair and apoptosis

Figure 4

Caspase inhibitors blocked apoptosis induced by agarose encapsulation. Representative PFGE from A431 and NP18 cell lines are depicted. Spontaneous DNA fragmentation induced exclusively by incubation in unirradiated cell-plugs (black bars) was inhibited (grey bars) by zvad-fmk (100 μM). *P = 0.016; **P = 0.083 (Mann-Whitney test, 4 independent experiments). No significant differences were found between the A431 and N18 cell lines.

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Radiation Oncology

ISSN: 1748-717X

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