Costunolide 5 μM | Cell cycle (%) | histone H3 (%) | mitotic index(%) | ||
---|---|---|---|---|---|
 | G1/G0 | S | G2/M |  |  |
control | 56.1 ± 0.7 | 26.8 ± 1.2 | 17.1 ± 1.5 | 3.6 ± 0.2 | 4.9 ± 0.7 |
2 h | 33.0 ± 0.1 | 37.3 ± 0.3 | 29.7 ± 0.3 | 14.8 ± 2.6 | 17.4 ± 1.6 |
4 h | 32.7 ± 0.7 | 33.1 ± 0.4 | 34.8 ± 0.5 | 25.8 ± 0.8 | 22.4 ± 4.1 |
16 h | 39.3 ± 1.7 | 26.7 ± 4.7 | 34.0 ± 3.2 | 15.2 ± 1.8 | 7.8 ± 1.0 |
24 h | 55.9 ± 2.1 | 15.2 ± 3.3 | 28.9 ± 1.2 | 8.2 ± 0.7 | 5.4 ± 0.7 |