Skip to main content

Table 1 Patient and treatment characteristics

From: The effect of bioequivalent radiation dose on survival of patients with limited-stage small-cell lung cancer

Characteristic Lower BED Group (≤57 Gy) Higher BED Group (>57 Gy) P
Patients(n) 70 135  
Age(years)    
Median 62 60 0.574
Range 38-83 35-81  
Gender    0.713
Male 57(81.4)* 107(79.3)  
Female 13(18.6) 28(20.7)  
KPS    
Median 80 80 0.163
Range 60-100 60-100  
Weight loss>5%    0.178
Yes 21(30.0) 29(21.5)  
No 49(70.0) 106(78.5)  
LDH    0.517
≤220 IU/L 35(43.1) 34(35.3)  
>220 IU/L 25(26.4) 78(22.6)  
Unknown 10(30.5) 23(42.1)  
ISN    0.190
Yes 8(11.4) 25(18.5)  
No 62(88.6) 110(81.5)  
CHT cycles    0.620
Median 4 6  
Range 3-8 3-7  
SER    0.951
Median 81 72  
Range 34-262 30-236  
BED(Gy)    0.000
Median 53.6 58.5  
Range 41.3-56.9 57.1-66.1  
TRT fractions    0.000
Once-daily 52(74.3) 23(17.0)  
Twice-daily 18(25.7) 112(83.0)  
TRT technique    0.418
2D 52(74.3) 107(79.3)  
3D 18(25.7) 28(20.7)  
Size of TRT field(cm3)#    0.722
Median 132 137  
Range 54-210 46-228  
PCI    0.199
Yes 11(15.7) 13(9.6)  
No 59(84.3) 122(90.4)  
  1. * Data in parentheses are percentages.
  2. # The size of equivalent square field at anterior-posterior axis
  3. Abbreviations: BED = biologically effective dose with time correction; KPS = Karnofsky performance score; LDH = lactate dehydrogenase; ISN = ipsilateral supraclavicular nodes; CHT = chemotherapy; SER = the time from the start of any treatment to the end of chest irradiation; TRT = thoracic radiation therapy; 2D = 2 dimension; 3D = 3 dimension; PCI = prophylactic cranial irradiation.