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Table 2 Enriched gene ontology terms for genes up-regulated in bleomycin sulphate treated fibroblasts compared to controls.

From: Gene expression profiling of human dermal fibroblasts exposed to bleomycin sulphate does not differentiate between radiation sensitive and control patients

Gene ontology term

a Number of genes

b EASE score

Establishment of localization

187

1.01E-08

Localization

187

1.49E-08

Cellular physiological process

514

7.47E-08

Secretion

31

7.61E-08

Transport

169

3.11E-07

Protein transport

51

3.81E-07

Establishment of protein localization

52

4.27E-07

Protein localization

52

1.06E-06

Apoptosis

49

1.96E-06

Programmed cell death

49

2.17E-06

Cell death

50

2.52E-06

Death

50

3.04E-06

Secretory pathway

24

4.45E-06

Intracellular transport

50

7.70E-06

Establishment of cellular localization

50

1.07E-05

Cellular localization

50

1.33E-05

Regulation of apoptosis

34

1.57E-05

Intracellular protein transport

32

1.74E-05

Regulation of programmed cell death

34

1.77E-05

Cell organization and biogenesis

98

1.81E-05

  1. All 16 fibroblast samples were included in the analysis. The top 20 terms for genes up-regulated after bleomycin sulphate are shown.
  2. aThe number of genes involved in the term are shown.
  3. bThe modified Fisher Exact p value (EASE score) is shown. The smaller the score, the more highly enriched the category.