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Figure 1 | Radiation Oncology

Figure 1

From: Investigation of tumor hypoxia using a two-enzyme system for in vitro generation of oxygen deficiency

Figure 1

Transcriptomics from HNO97 head and neck squamous cell carcinoma cells under normoxia and hypoxia. Gene expression pattern of known and validated HIF-1 target genes [15] before and after 24 h incubation under normoxic and hypoxic conditions (2% O2) using the enzymatic GOX/CAT system and a hypoxia chamber. The colour scale encodes differential regulation of genes from green (≤- 2-fold downregulated vs. reference normoxia t = 0 RNA) to red (≥+ 2-fold upregulated vs. reference normoxia t = 0 RNA).

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Radiation Oncology

ISSN: 1748-717X

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