Postmastectomy irradiation in breast in breast cancer patients with T1-2 and 1-3 positive axillary lymph nodes: Is there a role for radiation therapy?

Table 1 Clinical characteristics of patients undergoing modified radical mastectomy

Groups	Radiotherapy n = 66		No-Radiotherapy n = 24
Characteristic	n	(%)	n	(%)
Age, years
Median	51	48	50	50
Range	28-73		34-77
≤50	32		12
Postmenopausal status	37	56	13	54
Lymph nodes examined
Median	12		10
Range	(3-37)		(4-31)
Involved/dissected lymph nodes
Median	13	15	2	14
Range		(4-38)		(6-25)
≥ 25%		20		8
Extracapsular extension	26	39	10	42
Stage (Tumor size)
IIA (T1N1)	13	20	9	37.5
IIB (T2N1)	53	80	15	62.5
Tumor location
Medial	20	30	6	25
Central	16	24	6	25
Lateral	30	46	12	50
Histology
Ductal	53	80	18	75
Lobuler	3	5	2	8
Other (mixt, mucinous, medullary)	10	15	4	17
Histological Grade
I	10	15	8	33
II	39	59	11	41
III	17	26	5	26
Nuclear Grade
I	14	22	8	33
II	26	39	11	46
III	26	39	5	21
Invasion
Lymphatic	47	71	11	46
Vascular	42	64	13	54
Perineural	34	52	5	21
Receptors
Estrogen receptor	49	74	17	71
Progesteron receptor	51	77	17	71
Systemic therapies
Hormonotherapy	49	74	17	71
Chemotherapy	66	100	23	96

ISSN: 1748-717X