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Table 2 Relevant plan parameters of tangential beam IMRT versus tangential beam 3D-CRT of the adjuvant radiotherapy of the chest wall in unselected postmastectomy breast cancer patients.

From: Tangential beam IMRT versus tangential beam 3D-CRT of the chest wall in postmastectomy breast cancer patients: A dosimetric comparison

 

IMRT

3D-CRT

   

Organ

Parameter

Mean

1SD

Mean

1SD

Difference

Difference (%)

P value

Ipsilateral chest wall (PTV)

      

   Maximum Dose (cGy)

5530

146

5462

135

68

1

0.04

   Mean Dose (cGy)

5083

73

5038

70

44

1

0.04

   Homogeneity Index

0.73

0.15

0.77

0.11

-0.05

-6

n. s.

   Conformity Index

0.32

0.04

0.25

0.14

0.07

26

0.03

Heart*

       

   Maximum Dose (cGy)

3874

1729

4990

180

-1116

-22

n. s.

   Mean Dose (cGy)

704

295

877

272

-173

-20

0.03

   V70%

5.71

3.40

10.61

3.68

-4.90

-46

<0.03

Ipsilateral lung

       

   Mean Dose (cGy)

1129

188

1437

204

-308

-21

<0.01

   D30%

960

537

1695

875

-734

-43

<0.01

  1. 3D-CRT, three-dimensional conformal radiotherapy; IMRT, intensity-modulated radiotherapy; 1SD, standard deviation; V70%, percentage of tissue volume encompassed by the 70% isodose line (35 Gy); D30%, dose to 30% of the volume (PTV or Organs at risk); *, Patients with left-sided breast cancer only; n.s., not significant.