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Table 4 Radiation regimen, follow-up and toxicities in patients not receiving concurrent protease inhibitor

From: Acute toxicity of second generation HIV protease-inhibitors in combination with radiotherapy: a retrospective case series

#

F/U [weeks]

Region treated

Dose (fractionation) [cgy]

Complete RT regimen

Acute toxicity and CTC grade

1

6

Pelvis

5400 (180)

yes

fatigue 1, nocturia 1, proctitis 2, gastrointestinal bleed 3, dermatitis 2

2

6

vaginal cuff brachytherapy

4500 and 2500 HDR (180 and 500 HDR)

yes

 

3

18

Abdomen

5040 (180)

yes

fatigue 1, anorexia 1, nausea 1

4

13

thoracic spine

3000 (300)

yes

fatigue 1

5

29

Brain

5400 (180)

yes

pain 2, edema 2

6

44

prostate and SV

7800 (200)

yes

nocturia and urinary frequency and urgency 2, urinary retention 1

7

20

Brain

5300 (250 and 18 Gy gamma-knife boost)

yes

memory impairment 1, concentration impairment 1

8a

0

prostate and SV

7800 (200)

yes

dysuria and nocturia 2, urinary retention 1, constipation 1

8b

13

Pelvis

3780 and 1400 HDR (180 and 700 HDR)

no

fatigue 2, anorexia 1, dermatitis 2

8c

4

Pelvis

3000 and 1200 IORT (200 and 1200 HDR)

yes

fatigue 1, pain 1, nocturia 1, anorexia 1, proctitis 1, diarrhea 1

9

13

Brain

2400 (200)

yes

fatigue 2, pain 2,

10

5

brain (repeated)

2400 (200)

yes

fatigue 2, anorexia 1, constipation 1, dermatitis 1,

11

0

Testicles

2700 (180)

no, prescribed 4140

pain 1, constipation 1, dermatitis 1

  1. Patients are uniquely identified by numbers, repeated treatments on a patient are distinguished by a letter after the number.
  2. F/U = follow-up
  3. HDR = high dose radiation