Skip to main content

Table 3 Radiation regimen, follow-up and toxicities in patients receiving concurrent protease inhibitor

From: Acute toxicity of second generation HIV protease-inhibitors in combination with radiotherapy: a retrospective case series

#

F/U

[weeks]

Region treated

Dose (fractionation)

[cgy]

Complete RT regimen

Acute toxicity and CTC grade

1a

75

right breast

5800 (200)

yes

dermatitis 2, pruritis 1, hyperpigmentation 2, fatigue 1, pain 1

1b

0

pelvis

3600 (180)

no, prescribed 5400

fatigue 2, pain 2, nocturia 2, anorexia 1, proctitis 2

     

fatigue 1, pain 1, nocturia and urinary

2

9

pelvis and left vulva

4500 (180)

yes

frequency 1, dysuria 2, proctitis 1, diarrhea

     

1, mucosal drainage 1

3

36

right breast

5130 (270)

yes

fatigue 2, pain 3, dermatitis 1, hyperpigmentation 2

4

18

pelvis and anus

3000 (200)

yes

dysuria 1

5

82

prostate and SV

6720 (320)

yes

dysuria and nocturia and urinary frequency 2, anorexia 1, diarrhea 1, hematochezia 1

6

18

prostate and SV

8000 (200)

yes

nocturia and urinary frequency 2

7

7

prostate and SV

7800 (200)

yes

pain 1, dysuria and urinary frequency and incontinence 2, constipation 1, diarrhea 1

8

8

left lateral chest wall

3600 (300)

yes

dermatitis 1

9

38

brain

2000 (2000)

yes

none

10

25

head and neck

7000 (200)

yes

dermatitis 3, fatigue 3, dysphonia 1, xerostomia 2

11

21

brain

3000 (300)

yes

fatigue 2, pain 2, nausea 2, insomnia 2, anorexia 2, vomiting 2, ataxia 2

12

23

right neck and left axilla

3000 (200)

yes

fatigue 1, pain 1, dermatitis 1, dysgeusia 1, dysphonia 1, xerostomia 1

13a

147

right pelvis

3000 (250)

yes

fatigue 1

13b

13

right axilla and ulcerating skin lesion

3060 (180)

yes

dermatitis 2, drainage 3, pruritus 1

13c

7

right temple and subcutaneous skin lesion

3060 (180)

yes

dermatitis 2

14

19

brain

3000 (300)

yes

fatigue 1

15

86

right breast

6000 (200)

yes

dermatitis 1

     

fatigue 1, pain 2, nausea 1, nocturia and

16

85

pelvis

5040 (180)

yes

urinary frequency 1, anorexia 2, proctitis 1,

     

diarrhea 2, dermatitis 2

17

10

brain

3000 (300)

yes

altered mental status in intensive care throughout treatment

18

31

posterior scalp

1600 (400)

yes

none

  1. Patients are uniquely identified by numbers, repeated treatments on a patient are distinguished by a letter after the number.
  2. F/U = follow-up