Skip to main content

Table 6 Cox time-dependant Multivariate analysis for overall survival

From: Validation of the new graded prognostic assessment scale for brain metastases: a multicenter prospective study

Variable

P

HR

Low 95% CI

High 95% CI

GPA *

    

   1.5-4.0

 

1

  

   0-1 [0-2 months]

0.003

2.52

1.38

4.62

   0-1 [2-3 months]

0.79

1.09

0.57

2.09

   0-1 [> 3 months]

0.10

1.41

0.94

2.11

BSBM **

    

   ≥ 1

 

1

  

   0 [0-2 months]

< 0.001

3.62

2.02

6.51

   0 [2-3 months]

0.001

2.98

1.53

5.78

   0 [> 3 months]

0.76

1.10

0.60

2.02

RPA ***

    

   I-II

 

1

  

   III [0-2 months]

< 0.001

3.27

1.83

5.85

   III [2-3 months]

0.22

1.58

0.77

3.24

   III [> 3 months]

0.65

1.13

0.67

1.87

  1. *: GPA was adjusted on centers, primary site and its status (control)
  2. **: BSBM was adjusted on centers, primary site, its status (control), age and number of brain metastases
  3. ***: RPA was adjusted on centers, primary site and number of brain metastases