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Table 4 Univariate analysis of potential prognostic factors at repeat brain irradiation

From: Population-based outcomes after whole brain radiotherapy and re-irradiation in patients with metastatic breast cancer in the trastuzumab era

Variables

pvalue (log-rank test)

RPA at re-BRT

< 0.001

Craniotomy at initial BM

0.18

Craniotomy at re-BRT

0.99

Number of BM at re-BRT

0.001

HER2 status

0.66

Trastuzumab on or after BM*

0.12

Chemotherapy on or after BM*

0.33

ER status

0.87

Tumour grade

< 0.001

  1. * Refers to treatments given on or after the date of brain re-irradiation.
  2. Abbreviations: re-BRT = repeat brain irradiation, RPA = recursive partitioning analysis, HER2 = human epidermal growth factor receptor 2, BM = brain metastasis, ER = estrogen receptor
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Radiation Oncology

ISSN: 1748-717X

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