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Table 4 Univariate analysis of potential prognostic factors at repeat brain irradiation

From: Population-based outcomes after whole brain radiotherapy and re-irradiation in patients with metastatic breast cancer in the trastuzumab era

Variables pvalue (log-rank test)
RPA at re-BRT < 0.001
Craniotomy at initial BM 0.18
Craniotomy at re-BRT 0.99
Number of BM at re-BRT 0.001
HER2 status 0.66
Trastuzumab on or after BM* 0.12
Chemotherapy on or after BM* 0.33
ER status 0.87
Tumour grade < 0.001
  1. * Refers to treatments given on or after the date of brain re-irradiation.
  2. Abbreviations: re-BRT = repeat brain irradiation, RPA = recursive partitioning analysis, HER2 = human epidermal growth factor receptor 2, BM = brain metastasis, ER = estrogen receptor