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Table 3 Patient characteristics of 37 cases prior to re-irradiation

From: Population-based outcomes after whole brain radiotherapy and re-irradiation in patients with metastatic breast cancer in the trastuzumab era

Patient Characteristics prior to re-BRT

n =37

Age (years)

 

   Median

48

KPS

 

   < 70

10 (27%)

   ≥ 70

27 (73%)

ECOG

 

   0-1

12 (32%)

   2

20 (54%)

   3-4

5 (13%)

Number of lesions

 

   1-3

15 (40%)

   > 3

22 (59%)

Primary status

 

   Controlled

22 (59%)

   Uncontrolled

15 (40%)

Extracranial disease

 

   Brain only

10 (27%)

   Bone

6 (16%)

   Visceral

19 (51%)

   Other

2 (5%)

RPA at re-BRT

 

   1

12 (32%)

   2

10 (27%)

   3

15 (40%)

Chemotherapy at BM*

 

   Yes

19 (51%)

   No

18 (49%)

Trastuzumab at BM*

 

   Yes

6 (16%)

   No

31 (84%)

  1. * Refers to treatments given on or after the date of brain re-irradiation.
  2. Abbreviations: re-BRT = re-irradiation, RPA = recursive partitioning analysis, KPS = karnofsky performance status, ECOG = eastern cooperative oncology group performance status, BM = brain metastasis