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Table 1 Summary of references to published mammalian cell survival data measured in experiments at low LET

From: Theoretical analysis of the dose dependence of the oxygen enhancement ratio and its relevance for clinical applications

Ref.

Cells

Rad. type (LET)

α a /α h

(β a /β h )1/2

OER(D)

[30]

V79-379A

x-rays

1.4

3.8

↗

[31]

V79-379A

x-rays

2.0

3.6

↗

[32]

V79-753B

x-rays

3.9

2.8

↘

[25]

V79-379A

x-rays

  

→

[33]

V79-B

x-rays

  

↗

[28]

V79-171

x-rays

2.3

3.6

↗

[26]

V79

protons (0.7 keV/μm)

1.7

4.5

↗

 

V79

protons (1.9 keV/μm)

1.9

3.2

↗

 

V79

x-rays

3.6

2.5

↘

[34]

V79

x-rays

  

↘

[27]

V79

x-rays

3.2

3.1

→

[33]

V79

x-rays

  

→

 

CHO-6

x-rays

  

→

[35]

CHO-K1

60Co γ-rays

  

↗

 

CHO-xrs6

60Co γ-rays

  

↗

[36]

CHO-K1

x-rays

  

↗

[37]

CHL-F

60Co γ-rays

  

→

[38]

R1

x-rays

  

→

[39]

R1

x-rays

  

→

[40]

FSa-II

60Co γ-rays

1.6

2.8

↗

 

FSa-II

protons (1.9 keV/μm)

1.9

2.6

↗

[41]

T1

x-rays

5.0

2.3

↘

[33]

AA8

x-rays

  

↘

[42]

EMT6

60Co γ-rays

  

↗

[43]

B14 FAF28

60Co γ-rays

  

↘

[44]

U251

60Co γ-rays

4.0

2.5

↘

  1. For each reference the cell line, the radiation type, the ratios of the radiosensitivity parameters (if provided) under aerobic (a) and hypoxic (h) conditions and the OER behavior as a function of dose (↗ increases, ↘ decreases or → remains nearly constant with increasing single dose) are given. The low-LET range was chosen between 0.2 and 2 keV/μm.