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Table 1 Comparisons of clinicopathological factors of breast cancers between A-bomb survivor and control.

From: Significance of genomic instability in breast cancer in atomic bomb survivors: analysis of microarray-comparative genomic hybridization

Clinicopathological profile A-bomb survivors (n = 15) Control (n = 13) P-value
Mean age of onset (years old) 58.0 (52.6, 63.4) 55.5 (49.7, 61.4) 0.511)
Mean tumor size (cm) 24.7 (20.7, 28.8) 36.2 (20.2, 52.3) 0.151)
Histological subtype    
Papillo-tubular 9 4 0.292)
Solid-tubular 1 2  
Scirrhous 5 7  
Histological grade    
I 1 3 0.043)
II 5 7  
III 9 3  
Lymph node metastasis    
Positive 8 5 0.604)
Negative 4 4  
Unknown 3 4  
ER status    
Positive 7 8 0.264)
Negative 8 5  
PgR status    
Positive 7 8 0.434)
Negative 8 5  
HER2 amplification (FISH)    
Positive 7 2 0.044)
Negative 5 11  
No signal 3 0  
C-MYC amplification (FISH)    
Positive 9 2 0.094)
Negative 5 7  
No signal 1 4  
Mean total length of CNA (bp) 64,032,415
(29,443,979, 139,238,660)
23,924,175
(6,936,445, 82,515,771)
0.151)
Mean number of CNA 12.2 (8.4, 16.0) 8.08 (3.0, 13.1) 0.161)
  1. †: 95% confidence interval, CNA: copy number aberrations
  2. 1): t-test, 2): χ2-test, 3): Cochran-Armitage test, 4): Fisher's exact test