Skip to main content

Table 1 Comparisons of clinicopathological factors of breast cancers between A-bomb survivor and control.

From: Significance of genomic instability in breast cancer in atomic bomb survivors: analysis of microarray-comparative genomic hybridization

Clinicopathological profile

A-bomb survivors (n = 15)

Control (n = 13)

P-value

Mean age of onset (years old)

58.0 (52.6, 63.4)†

55.5 (49.7, 61.4)

0.511)

Mean tumor size (cm)

24.7 (20.7, 28.8)

36.2 (20.2, 52.3)

0.151)

Histological subtype

   

Papillo-tubular

9

4

0.292)

Solid-tubular

1

2

 

Scirrhous

5

7

 

Histological grade

   

I

1

3

0.043)

II

5

7

 

III

9

3

 

Lymph node metastasis

   

Positive

8

5

0.604)

Negative

4

4

 

Unknown

3

4

 

ER status

   

Positive

7

8

0.264)

Negative

8

5

 

PgR status

   

Positive

7

8

0.434)

Negative

8

5

 

HER2 amplification (FISH)

   

Positive

7

2

0.044)

Negative

5

11

 

No signal

3

0

 

C-MYC amplification (FISH)

   

Positive

9

2

0.094)

Negative

5

7

 

No signal

1

4

 

Mean total length of CNA (bp)

64,032,415

(29,443,979, 139,238,660)

23,924,175

(6,936,445, 82,515,771)

0.151)

Mean number of CNA

12.2 (8.4, 16.0)

8.08 (3.0, 13.1)

0.161)

  1. †: 95% confidence interval, CNA: copy number aberrations
  2. 1): t-test, 2): χ2-test, 3): Cochran-Armitage test, 4): Fisher's exact test