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Table 1 Tumor type and size-dependency of [18F]FAZA in CT26 colon carcinomas and PyV-mT mammary carcinomas

From: Significant impact of different oxygen breathing conditions on noninvasive in vivo tumor-hypoxia imaging using [18F]-fluoro-azomycinarabino-furanoside ([18F]FAZA)

Tumor Tumor size 1 h p.i. 2 h p.i. 3 h p.i.
PyV-mT (n = 20) 0.982 ± 0.958 cm3 1.31 ± 0.71 1.06 ± 0.69 0.92 ± 0.61
CT26 (n = 10) 0.279 ± 0.086 cm3 1.53 ± 0.43 1.14 ± 0.37 0.84 ± 0.26
PyV-mT (n = 12) 0.15 - 0.50 cm3 1.47 ± 0.89 1.13 ± 0.83 0.97 ± 0.70
PyV-mT (n = 4) 0.5 - 1.5 cm3 1.22 ± 0.59 1.05 ± 0.61 0.91 ± 0.56
PyV-mT (n = 4) > 1.5 cm3 1.15 ± 0.41 0.86 ± 0.36 0.76 ± 0.42
CT26 (n = 4) < 0.15 cm3 1.37 ± 0.41 0.92 ± 0.38 0.68 ± 0.38
CT26 (n = 6) 0.15 - 0.50 cm3 1.58 ± 0.45 1.22 ± 0.35 0.90 ± 0.22
  1. Data are presented as %ID/cc ± SD. h: hour, p.i.: post injection. PyV-mT n = 9 mice, n = 20 tumors.