Table 2 ABZ induces a lower SF2 (ie supra-additive) than the expected added SF2 (EAS) calculated by adding the effect of radiation alone and ABZ alone.
From: Albendazole sensitizes cancer cells to ionizing radiation
| Â | Â | % Survival | Â | |
|---|---|---|---|---|
Cell line | ABZ (nM) | 0 Gy | 2 Gy | EAS |
A375 | 0 | 100 | 61.6 | Â |
| Â | 100 | 101.3 | 57.8 | Â |
| Â | 500 | 93.2 | 28.1 | 53.8 |
A2058 | 0 | 100 | 85.0 | Â |
| Â | 100 | 93.4 | 76.2 | Â |
| Â | 500 | 80.2 | 56.8 | 64.8 |
H1530 | 0 | 100 | 62.8 | Â |
| Â | 100 | 89.4 | 58.9 | Â |
| Â | 500 | 80.5 | 37.1 | 43.3 |
H446 | 0 | 100 | 84.7 | Â |
| Â | 100 | 92.6 | 73.3 | Â |
| Â | 500 | 75.6 | 54.5 | 60.3 |