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Table 2 Results of log-rank tests

From: Impact of pathological tumor stage for salvage radiotherapy after radical prostatectomy in patients with prostate-specific antigen < 1.0 ng/ml

Factor

4-year bRFS (%) (95% CI)

p value

Pathologic tumor stage

 

< 0.001

T1-2

79.2 (66.0-92.3)

 

T3-4

31.7 (17.0-46.4)

 

Surgical margin

 

0.652

Positive

48.6 (32.0-65.1)

 

Negative

57.1 (42.7-71.4)

 

Gleason score

 

0.189

≤ 7

58.9 (44.5-73.3)

 

≥ 8

35.2 (14.7-51.5)

 

Preoperative PSA (ng/ml)

 

0.037

< 10

62.0 (47.7-76.3)

 

≥ 10

39.3 (22.5-56.0)

 

Pre-RT PSA (ng/ml)

 

0.620

< 0.25

54.5 (37.5-71.6)

 

≥ 0.25

45.9 (30.2-64.9)

 

PSA doubling time (months)

 

0.059

< 7

34.6 (17.5-51.8)

 

≥ 7

62.2 (46.7-77.7)

 

RT dose (Gy)

 

0.068

< 64

36.8 (15.2-58.5)

 

≥ 64

51.7 (37.6-65.9)

 

BED (Gy) (α/β = 1.5)

 

0.213

< 145

41.4 (23.5-59.3)

 

≥ 145

54.3 (39.5-69.1)

 

Time from RP to RT (months)

 

0.310

< 24

45.2 (29.1-61.4)

 

≥ 24

57.4 (40.9-73.9)

 

Hormone therapy

 

0.627

Done

50.5 (20.2-72.9)

 

Not done

50.7 (37.6-63.7)

 
  1. Abbreviations: bRFS = biochemical relapse-free survival, RT = radiotherapy, PSA = prostate-specific antigen, BED = biological effective dose, RP = radical prostatectomy, CI = confidence interval