Skip to main content

Table 3 Comparisons of the DVH-based parameters of the OARsain present study (n = 12).

From: Planning analysis for locally advanced lung cancer: dosimetric and efficiency comparisons between intensity-modulated radiotherapy (IMRT), single-arc/partial-arc volumetric modulated arc therapy (SA/PA-VMAT)

 

IMRT

SA-VMAT

PA-VMAT

 

mean ± SD

mean ± SD

p value b

mean ± SD

p value c

p value d

Total lungs

      

   V5e (%)

50.6 ± 10.6

59.7 ± 10.8

0.048

59.3 ± 9.1

0.042

0.923

   V10e (%)

40.2 ± 7.2

46.9 ± 8.3

0.046

46.4 ± 7.3

0.048

0.877

   V20e (%)

25.7 ± 5.7

21.1 ± 4.8

0.044

20.3 ± 4.4

0.016

0.675

   V30e (%)

15.8 ± 3.4

12.9 ± 3.2

0.043

12.5 ± 3.2

0.023

0.876

   MLDf (Gy)

14.4 ± 2.3

12.5 ± 2.2

0.047

12.3 ± 2.2

0.028

0.785

Contralateral lungs

   V5 (%)

44.7 ± 10.7

55.2 ± 11.9

0.033

53.8 ± 9.4

0.038

0.752

   V10 (%)

32.1 ± 7.1

39.4 ± 9.8

0.048

38.5 ± 7.3

0.041

0.801

   V20 (%)

13.8 ± 4.4

10.2 ± 4.1

0.046

7.5 ± 2.2

< 0.01

0.048

   V30 (%)

3.3 ± 1.9

2.0 ± 1.0

0.048

1.3 ± 0.6

< 0.01

0.049

   MLD (Gy)

9.6 ± 1.2

8.7 ± 1.0

0.038

7.8 ± 1.0

< 0.01

0.038

Ipsilateral lungs

   V5 (%)

67.6 ± 10.5

68.9 ± 11.8

0.778

72.4 ± 13.7

0.346

0.052

   V10 (%)

56.8 ± 9.1

57.3 ± 9.7

0.898

61.1 ± 11.5

0.321

0.167

   V20 (%)

43.9 ± 5.8

45.2 ± 6.3

0.604

43.1 ± 5.2

0.725

0.383

   V30 (%)

29.8 ± 1.2

29.9 ± 1.4

0.853

29.5 ± 1.2

0.547

0.460

   MLD (Gy)

18.8 ± 2.98

20.2 ± 2.9

0.264

18.3 ± 2.8

0.728

0.141

Spinal cord

      

   Dmaxf (Gy)

43.0 ± 2.5

41.6 ± 2.5

0.194

42.5 ± 2.4

0.603

0.404

   D5g (Gy)

40.3 ± 3.8

39.8 ± 3.9

0.711

40.1 ± 3.9

0.891

0.837

Heart

      

   V30e (%)

20.9 ± 5.7

20.8 ± 5.8

0.973

21.2 ± 6.3

0.894

0.870

   V40e (%)

14.6 ± 5.5

13.4 ± 5.5

0.595

15.0 ± 5.9

0.859

0.788

   Dmeanf (Gy)

14.8 ± 7.7

14.4 ± 7.4

0.915

15.1 ± 7.5

0.903

0.818

Esophagus

      

   V55e (%)

12.4 ± 7.3

12.3 ± 7.5

0.971

13.6 ± 8.3

0.707

0.685

   Dmeanf (Gy)

22.4 ± 5.6

21.9 ± 5.2

0.811

23.7 ± 6.3

0.609

0.455

  1. a: organs at-risk; b: compared with the parameters of IMRT; c: compared with the parameters of IMRT; d: compared with the parameters of SA-VMAT; e: the volume of the lung that received the 5, 10, 20, 30, 40 and 55 Gy irradiation dose, respectively; f: the maximum or mean irradiation dose that the lung, spinal cord, heart and esophagus received, respectively; g: the irradiation dose that the 5% volume of the spinal cord received.
Back to article page

Radiation Oncology

ISSN: 1748-717X

Contact us