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Table 3 Comparisons of the DVH-based parameters of the OARsain present study (n = 12).

From: Planning analysis for locally advanced lung cancer: dosimetric and efficiency comparisons between intensity-modulated radiotherapy (IMRT), single-arc/partial-arc volumetric modulated arc therapy (SA/PA-VMAT)

  IMRT SA-VMAT PA-VMAT
  mean ± SD mean ± SD p value b mean ± SD p value c p value d
Total lungs       
   V5e (%) 50.6 ± 10.6 59.7 ± 10.8 0.048 59.3 ± 9.1 0.042 0.923
   V10e (%) 40.2 ± 7.2 46.9 ± 8.3 0.046 46.4 ± 7.3 0.048 0.877
   V20e (%) 25.7 ± 5.7 21.1 ± 4.8 0.044 20.3 ± 4.4 0.016 0.675
   V30e (%) 15.8 ± 3.4 12.9 ± 3.2 0.043 12.5 ± 3.2 0.023 0.876
   MLDf (Gy) 14.4 ± 2.3 12.5 ± 2.2 0.047 12.3 ± 2.2 0.028 0.785
Contralateral lungs
   V5 (%) 44.7 ± 10.7 55.2 ± 11.9 0.033 53.8 ± 9.4 0.038 0.752
   V10 (%) 32.1 ± 7.1 39.4 ± 9.8 0.048 38.5 ± 7.3 0.041 0.801
   V20 (%) 13.8 ± 4.4 10.2 ± 4.1 0.046 7.5 ± 2.2 < 0.01 0.048
   V30 (%) 3.3 ± 1.9 2.0 ± 1.0 0.048 1.3 ± 0.6 < 0.01 0.049
   MLD (Gy) 9.6 ± 1.2 8.7 ± 1.0 0.038 7.8 ± 1.0 < 0.01 0.038
Ipsilateral lungs
   V5 (%) 67.6 ± 10.5 68.9 ± 11.8 0.778 72.4 ± 13.7 0.346 0.052
   V10 (%) 56.8 ± 9.1 57.3 ± 9.7 0.898 61.1 ± 11.5 0.321 0.167
   V20 (%) 43.9 ± 5.8 45.2 ± 6.3 0.604 43.1 ± 5.2 0.725 0.383
   V30 (%) 29.8 ± 1.2 29.9 ± 1.4 0.853 29.5 ± 1.2 0.547 0.460
   MLD (Gy) 18.8 ± 2.98 20.2 ± 2.9 0.264 18.3 ± 2.8 0.728 0.141
Spinal cord       
   Dmaxf (Gy) 43.0 ± 2.5 41.6 ± 2.5 0.194 42.5 ± 2.4 0.603 0.404
   D5g (Gy) 40.3 ± 3.8 39.8 ± 3.9 0.711 40.1 ± 3.9 0.891 0.837
Heart       
   V30e (%) 20.9 ± 5.7 20.8 ± 5.8 0.973 21.2 ± 6.3 0.894 0.870
   V40e (%) 14.6 ± 5.5 13.4 ± 5.5 0.595 15.0 ± 5.9 0.859 0.788
   Dmeanf (Gy) 14.8 ± 7.7 14.4 ± 7.4 0.915 15.1 ± 7.5 0.903 0.818
Esophagus       
   V55e (%) 12.4 ± 7.3 12.3 ± 7.5 0.971 13.6 ± 8.3 0.707 0.685
   Dmeanf (Gy) 22.4 ± 5.6 21.9 ± 5.2 0.811 23.7 ± 6.3 0.609 0.455
  1. a: organs at-risk; b: compared with the parameters of IMRT; c: compared with the parameters of IMRT; d: compared with the parameters of SA-VMAT; e: the volume of the lung that received the 5, 10, 20, 30, 40 and 55 Gy irradiation dose, respectively; f: the maximum or mean irradiation dose that the lung, spinal cord, heart and esophagus received, respectively; g: the irradiation dose that the 5% volume of the spinal cord received.