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Table 1 Association between GP96 overexpression and clinicopathological parameters

From: GP96 is over-expressed in oral cavity cancer and is a poor prognostic indicator for patients receiving radiotherapy

 

Total patients

GP96 over-expression

 
   

No

Yes

 
 

No.

%

No.

%

No.

%

P

Gender

      

0.518*

   Male

77

97.5

23

30

54

70

 

   Female

2

2.5

1

50

1

50

 

Age (years)

      

0.573

   ≤ 48

44

51

11

27.5

29

72.5

 

   > 48

39

49

13

33

26

67

 

Smoking

      

0.573*

   No

14

18

4

29

10

71

 

   Yes

65

82

20

31

45

69

 

Drinking

      

0.237

   No

19

24

4

21

15

79

 

   Yes

60

76

20

33

40

67

 

Betel-quid chewing

      

0.427*

   No

14

18

5

36

9

64

 

   Yes

65

82

19

29

46

71

 

Stage

      

0.349*

   I-II

13

16.5

5

38.5

8

61.5

 

   III-IV

66

83.5

19

29

47

71

 

T stage

      

0.390

   T1-2

36

46

12

33

24

67

 

   T3-4

43

54

12

28

31

72

 

Nodal stage

      

0.020

   N0-1

44

56

18

41

26

59

 

   N2

35

44

6

17

29

83

 

Nodal ECS

      

0.183

   No

45

57

16

33

29

67

 

   Yes

34

43

8

23.5

26

76.5

 

Differentiation

      

0.654

   Well

24

30

9

37.5

15

62.5

 

   Moderate

47

60

13

28

34

72

 

   Poor

8

10

2

25

6

75

 

Depth (millimeters)

      

0.045

   ≤10

30

38

13

43

17

57

 

   > 10

49

62

11

22

38

78

 

Skin invasion

      

0.641*

   No

72

91

22

31

50

69

 

   Yes

7

9

2

29

5

71

 

Bone invasion

      

0.402

   No

56

71

18

32

38

68

 

   Yes

23

29

6

26

17

74

 

Perineural invasion

      

0.424

   No

53

67

15

28

38

72

 

   Yes

24

30

8

33

16

67

 

   Missing

2

3

     

Blood Vessel invasion

       

   No

72

91

22

31

50

69

0.528*

   Yes

5

6

1

20

4

80

 

   Missing

2

3

     

Lymphatic vessel invasion

      

0.069*

   No

65

82

22

34

43

66

 

   Yes

12

15

1

8

11

92

 

   Missing

2

3

     

Margin status (millimeters)

      

0.605*

   ≥ 5

66

83.5

20

30

46

70

 

   < 5

13

16.5

4

31

9

69

 
  1. * Fisher's exact test
  2. Abbreviations: ECS = extracapsular spreading