Table 6 Multivariate analysis for LRRFS, DMFS, and DFS

Age

   (> 40 vs. ≤40)

0.62 (0.07-5.27)

0.07 (0.01-0.80)

0.22 (0.04-1.36)

p = 0.664

p = 0.033

p = 0.104

T stage

   (2-3 vs. 1)

1.02 (0.11-9.02)

6.09 (0.83-44.72)

2.58 (0.52-12.82)

p = 0.989

p = 0.076

p = 0.247

NR

   (> 0.15 vs. ≤0.15)

7.38 (0.89-61.25)

11.22 (1.70-74.04)

5.06 (1.05-24.37)

p = 0.064

p = 0.012

p = 0.043

Histologic grade

   (3 vs. 1-2)

5.86 (0.48-71.23)

1.26 (0.22-7.33)

1.33 (0.28-6.30)

p = 0.166

p = 0.795

p = 0.724

LVI

   (positive vs. negative or unknown)

0.90 (0.10-8.14)

0.38 (0.06-2.32)

0.71 (0.15-3.25)

p = 0.927

p = 0.294

p = 0.654

RM

   (close or positive vs. negative)

1.36 (0.08-22.32)

1.87 (0.22-16.26)

1.62 (0.23-11.30)

p = 0.829

p = 0.569

p = 0.624

Surgery

   (MRM vs. BCS)

4.62 (0.37-57.31)

0.57 (0.87-3.78)

1.21 (0.24-6.22)

p = 0.234

p = 0.563

p = 0.819

Regional RT

   (yes vs. no)

1.70 (0.12-24.18)

0.64 (0.06-6.95)

0.59 (0.06-5.92)

p = 0.695

p = 0.717

p = 0.653

Chemotherapy

   (yes vs. no)

0.17 (0.01-5.22)

0.15 (0.01-1.68)

0.27 (0.03-2.41)

p = 0.311

p = 0.125

p = 0.243