Table 3 Survival between Treatment Groups by Patient, Tumor, and Treatment Characteristics
| Â | No. of Patients, (%) | Overall Survival, Median, mo | 5-year Survival, Percent | ||||
|---|---|---|---|---|---|---|---|
| Â | Observation | Adjuvant CRT | Observation | Adjuvant CRT | P-value | Observation | Adjuvant CRT |
ALL PATIENTS | 120 (64.5) | 66 (35.5) | 39.9 | 40.1 | 0.839 | 37.2 | 42.1 |
Age, yrs | Â | Â | Â | Â | Â | Â | Â |
   < 75 | 79 (57.7) | 58 (42.3) | 41.3 | 40.6 | 0.913 | 37.9 | 45.9 |
   ≥ 75 | 41 (83.7) | 8 (16.3) | 35.5 | 33.3 | 0.939 | 36.0 | 25.0 |
Gender | Â | Â | Â | Â | Â | Â | Â |
   Female | 54 (70.1) | 23 (20.9) | 42.7 | 32.1 | 0.162 | 40.8 | 29.3 |
   Male | 66 (60.6) | 43 (39.4) | 32.2 | 46.0 | 0.238 | 33.9 | 48.4 |
Institution | Â | Â | Â | Â | Â | Â | Â |
   Mayo | 63 (76.8) | 19 (23.2) | 38.2 | 62.4 | 0.599 | 35.5 | 51.3 |
   Hopkins | 57 (54.8) | 47 (45.2) | 41.7 | 36.5 | 0.890 | 40.0 | 37.0 |
Histology | Â | Â | Â | Â | Â | Â | Â |
   Grade 1/2 | 60 (70.6) | 25 (29.4) | 53.6 | 62.2 | 0.328 | 47.1 | 56.6 |
   Grade 3 | 60 (59.4) | 41 (40.6) | 34.9 | 27.1 | 0.985 | 27.5 | 34.1 |
Node | Â | Â | Â | Â | Â | Â | Â |
   Negative | 84 (82.4) | 18 (17.7) | 61.6 | 103.2 | 0.122 | 52.4 | 87.1 |
   Positive | 36 (42.9) | 48 (57.1) | 15.7 | 32.1 | 0.004 | 5.9 | 27.5 |
Tumor Stage | Â | Â | Â | Â | Â | Â | Â |
   T1/T2 | 83 (74.8) | 28 (25.2) | 41.3 | 87.5 | 0.172 | 41.7 | 56.8 |
   T3/T4 | 37 (49.3) | 38 (50.7) | 27.0 | 25.0 | 0.873 | 27.5 | 28.7 |
Tumor Size | Â | Â | Â | Â | Â | Â | Â |
   ≤ 3 cm | 81 (67.5) | 39 (32.5) | 41.3 | 36.5 | 0.797 | 38.8 | 40.0 |
   > 3 cm | 39 (59.1) | 27 (40.9) | 27.0 | 40.6 | 0.496 | 33.9 | 44.0 |
Margin status | Â | Â | Â | Â | Â | Â | Â |
   Negative | 120 (65.6) | 63 (34.4) | 40.1 | 39.9 | 0.754 | 37.2 | 42.7 |
   Positive | 0 (0.0) | 3 (100.0) | N/A | 33.3 | N/A | N/A | 33.3 |