Table 2 Associations of Overall Survival with Patient Tumor and Treatment Characteristics
| Â | No. (%) | 2-Year Survival, % | 5-year Survival, % | Median Survival, months | Univariate RR (95% CI) | P-value |
|---|---|---|---|---|---|---|
Age, yrs | Â | Â | Â | Â | Â | Â |
   < 75 | 137 (73.7) | 66.5 | 41.2 | 40.6 | 1.00 | 0.281 |
   ≥ 75 | 49 (26.3) | 66.7 | 32.5 | 35.5 | 1.27 (0.82 - 1.98) |  |
Gender | Â | Â | Â | Â | Â | Â |
   Female | 77 (41.4) | 67.4 | 37.4 | 39.9 | 1.00 | 0.954 |
   Male | 109 (58.6) | 66.0 | 40.4 | 36.5 | 0.99 (0.67 - 1.47) |  |
Institution | Â | Â | Â | Â | Â | Â |
   Mayo Clinic | 82 (44.1) | 68.6 | 39.9 | 40.6 | 1.00 | 0.350 |
   JHH | 104 (55.9) | 64.8 | 38.9 | 36.9 | 1.20 (0.81 - 1.78) |  |
T stage | Â | Â | Â | Â | Â | Â |
   1/2 | 111 (59.7) | 75.0 | 46.3 | 55.4 | 1.00 | 0.002 |
   3/4 | 75 (40.3) | 54.1 | 28.1 | 27.0 | 1.86 (1.26 - 2.75) |  |
Tumor Size | Â | Â | Â | Â | Â | Â |
   ≤ 3 cm | 120 (64.5) | 72.5 | 39.3 | 40.1 | 1.00 | 0.838 |
   > 3 cm | 66 (35.5) | 56.5 | 38.3 | 35.5 | 1.04 (0.70 - 1.55) |  |
Node Status | Â | Â | Â | Â | Â | Â |
   Negative | 102 (54.8) | 84.1 | 58.7 | 79.4 | 1.00 | <0.001 |
   Positive | 84 (45.2) | 47.2 | 18.4 | 23.0 | 3.18 (2.11 - 4.78) |  |
Histology | Â | Â | Â | Â | Â | Â |
   Grade 1/2 | 85 (45.7) | 75.8 | 49.9 | 60.0 | 1.00 | 0.011 |
   Grade 3 | 101 (54.3) | 59.1 | 30.6 | 32.1 | 1.69 (1.13 - 2.53) |  |
Margin Status | Â | Â | Â | Â | Â | Â |
   Negative | 183 (98.4) | 66.6 | 39.3 | 39.9 | 1.00 | 0.493 |
   Positive | 3 (1.6) | 33.3 | 0.0 | 33.3 | 1.49 (0.47 - 4.72) |  |
Adjuvant Treatment | Â | Â | Â | Â | Â | Â |
   None | 120 (64.5) | 67.3 | 37.2 | 40.1 | 1.00 | 0.839 |
   CRT* | 66 (35.5) | 65.3 | 42.1 | 39.9 | 0.96 (0.64 - 1.43) |  |