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Table 1 Baseline Characteristics between Treatment Groups

From: Evaluation of adjuvant chemoradiation therapy for ampullary adenocarcinoma: the Johns Hopkins Hospital - Mayo Clinic collaborative study

 

Observation Only

N = 120

Adjuvant Chemoradiation (CRT) Therapy

N = 66

P-Value

DEMOGRAPHIC

   

Age at Surgery (yr)

   

   Mean, (SD*)

68.9 (11.6)

62.0 (10.8)

<0.001

   Median (Range)

71.3 (28.7-90.3)

63.3 (29.3-81.5)

 

Gender

   

   Male, No. (%)

66 (55.0)

43 (65.2)

0.179

Institution

   

   Mayo Clinic

63 (52.5)

19 (28.8)

0.002

   Johns Hopkins Hospital (JHH)

57 (47.5)

47 (71.2)

 

TUMOR CHARACTERISTCS

   

T Stage

   

   1

37 (30.8)

8 (12.1)

0.002

   2

46 (38.3)

20 (30.3)

 

   3

33 (27.5)

34 (51.5)

 

   4

4 (3.3)

4 (6.1)

 

Tumor Diameter

   

   < 3 cm

81 (67.5)

39 (59.1)

0.251

   ≥ 3 cm

39 (32.5)

27 (40.9)

 

Nodal Status

   

   N0

84 (70.0)

18 (27.3)

<0.001

   N1

36 (30.0)

48 (72.3)

 

Histologic Grading

   

   1

8 (6.7)

0 (0.0)

0.053

   2

52 (43.3)

25 (37.9)

 

   3

60 (50.0)

41 (62.1)

 

Surgical Margins

   

   Positive

0 (0.0)

3 (4.6)

0.019

   Negative

120 (100.0)

63 (95.4)

 
  1. *SD = standard deviation