Phospho-ERK and AKT status, but not KRAS mutation status, are associated with outcomes in rectal cancer treated with chemoradiotherapy

Table 1 Patient characteristics and clinical data

Characteristics		N = 70
Age at diagnosis	Median	58 years
	Range	26-89
Gender	Male	42 (60%)
	Female	28 (40%)
Race	White	52 (74%)
	Black	15 (21%)
	Other or unknown	3 (4%)
Clinical disease stage (at diagnosis)	II	25 (36%)
	III	39 (56%)
	IV	6 (9%)
Pathological disease response	Complete response (pCR)	12 (17%)
	Major response (pMR)	13 (19%)
	Limited response (pLR)	45 (64%)
Treatment response	Downstaged	30 (43%)
	No change	33(47%)
	Upstaged	7 (10%)
Recurrence	No	45 (64%)
	Yes	25 (36%)
	Local recurrence	7 (10%)
	Distant recurrence	13 (19%)
	Both local and distant	5 (7%)
Status (censored April 23, 2008)	Alive	41 (59%)
	Dead	29 (41%)

ISSN: 1748-717X