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Table 3 Multivariate analysis of clinical variables for LMS and OS

From: Prognosticators and Risk Grouping in Patients with Lung Metastasis from Nasopharyngeal Carcinoma: A more accurate and appropriate assessment of prognosis

Clinical     
endpoint Variable HR 95% CI P value *
LMS Age 1.659 1.107 to 2.484 0.014
  VCA-IgA 1.518 1.012 to 2.277 0.043
  Site of metastases 1 1.033 0.606 to 1.757 0.906
  Number of metastases 2 1.585 1.013 to 2.481 0.044
  Secondary metastases 3 3.132 1.948 to 5.036 <0.001
OS Age 1.906 1.355 to 2.682 <0.001
  AJCC T classification 1.530 1.074 to 2.177 0.018
  AJCC N classification 1.622 1.149 to 2.289 0.006
  Site of metastases 1 1.464 1.023 to 2.095 0.037
  Number of metastases 2 1.079 0.630 to 1.848 0.782
  Secondary metastases 3 2.343 1.585 to 3.462 <0.001
  DFI 5.050 3.356 to 7.576 <0.001
  1. Abbreviation: LMS: lung metastasis survival; OS: overall survival; AJCC: American Joint Committee Cancer; DFI: disease-free interval; HR: hazard ratio; 95% CI: 95% confidence interval.
  2. 1 Unilateral vs. Bilateral; 2 Solitary vs. Multiple; 3 Absent vs. Present
  3. * Cox proportional hazards regression models.