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Table 5 Univariate analysis for factors associated with ≥ grade3 acute toxicity

From: Helical tomotherapy in the treatment of pediatric malignancies: a preliminary report of feasibility and acute toxicity

Characteristic

 

Grade 0-2

Grade 3-4

P value

Total dose*

 

43,1 (15,4)

52,0 (7,6)

0,005§

Age§

 

5,4 (+/- 3,1)

7,1 (+/- 4,2)

0,12

Craniospinal irradiation

Yes

8 (18%)

16 (78%)

< 0,001

 

No

36 (82%)

6 (27%)

 

Chemotherapy

Yes

33 (79%)

19 (86%)

0,52

 

No

9 (21%)

3 (14%)

 
  1. * Asymmetric distribution verified by Kolmogorov-Smirnov test. Mann-Whitney test performed.
  2. § Chi-square test.
  3. t-test