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Table 5 Univariate analysis for factors associated with ≥ grade3 acute toxicity

From: Helical tomotherapy in the treatment of pediatric malignancies: a preliminary report of feasibility and acute toxicity

Characteristic   Grade 0-2 Grade 3-4 P value
Total dose*   43,1 (15,4) 52,0 (7,6) 0,005§
Age§   5,4 (+/- 3,1) 7,1 (+/- 4,2) 0,12
Craniospinal irradiation Yes 8 (18%) 16 (78%) < 0,001
  No 36 (82%) 6 (27%)  
Chemotherapy Yes 33 (79%) 19 (86%) 0,52
  No 9 (21%) 3 (14%)  
  1. * Asymmetric distribution verified by Kolmogorov-Smirnov test. Mann-Whitney test performed.
  2. § Chi-square test.
  3. t-test