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Table 1 Reference for planning of pituitary adenoma and meningioma

From: Quantitative assessment of inter-observer variability in target volume delineation on stereotactic radiotherapy treatment for pituitary adenoma and meningioma near optic tract

 

Pituitary adenoma

Meningioma

PTV definitions

 

PTV = CTV + 1 mm (CTV = GTV),

PTV = CTV + 1 mm (CTV = GTV)

 

PTV = CTV + 2 - 4 mm (CTV = GTV)

PTV = CTV + 2 - 3 mm (CTV = GTV)

Prescribed dose

SRS

15 - 20 Gy marginal dose, 25 Gy or more for secreting pituitary adenoma

11 - 18 Gy marginal dose (recommended for 14 Gy or more)

Conventional fractionated SRT

 

isocenter 45 - 68 Gy/daily 1.8 Gy/fr., D95 50 - 56 Gy/daily 2 Gy/fr.

SRT

45 - 50 Gy/25 - 28 fr.

2 Gy/fr.

Constrains for organs at risk [11]

  

SRS

Optic tract < 8 - 10 Gy,

 

Conventional fractionated

  

SRT

Optic tract 50 Gy/25 fr

 
 

Spinal cord < 50 Gy (10 cm or less in length)

 
 

Retina < 45 Gy

 
 

Lens < 10 Gy

 
 

Brain stem < 60 Gy (1/3 volume)

 
  1. SRS; stereotactic radiosurgery, SRT; stereotactic radiotherapy,
  2. GTV; gross tumor volume, CTV; clinical treatment volume, PTV; planning target volume, fr.; fraction,
  3. D95; irradiation dose that included 95% volume of PTV