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Table 6 Results from selected series regarding late toxicity in head and neck cancer patients treated with RT ± chemotherapy

From: Dysphagia in head and neck cancer patients following intensity modulated radiotherapy (IMRT)

Technique

Authors [reference]

year

No of patients

median follow up (months)

stage lll/lV (%)

Chemotherapy (%)

grade 3/4 late toxicity

 

Chao et al [25]

2003

74

30

93

23

0

I

       
 

de Arruda et al [14]

2006

50

18

92

86

3 (6%)

M

       
 

Lee et al [17]

2006

41

31

100

100

5 (12%)

R

       
 

Studer et al [1]

2006

115

18

52

78

18 (15%)

T

       
 

present study

2010

81*

55

100

85

7 (9%)

 

Denis et al [26]

2003

44

60

100

61

30 (68%)

3D-CRT

       
 

Huguenin et al [19]

2004

224

39

97

50

G3: 92 (41%)

       

G4: 5 ("%)

  1. Abbreviations: IMRT: Intensity modulated radiation therapy; 3D-CRT: three-dimensional conformal radiotherapy (*patient with previous Cobalt radiation therapy excluded)