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Table 1 Results of recent clinical experience with Interstitial brachytherapy with more than 5 years follow up

From: Accelerated Partial Breast Irradiation (APBI): A review of available techniques

Author No of cases Follow up interval (years) Dose rate/pt no Scheme Total dose (Gy) 5-year LR (%) Good/Excellent cosmesis
Strnad et al.[60] 274 5.25 PDR/HDR PDR = 0.6 Gy/hr HDR = 4 Gy x8 PDR = 50 Gy HDR = 32 Gy 2.9% 90%
Antonucci et al. [59] 199 9.6 LDR/HDR LDR 0.52 Gy/h × 96 hours HDR = 4 Gy x8 HDR = 3.4 Gyx10 LDR = 50 Gy HDR = 32 Gy HDR = 34 Gy 5% 99%
Johansson et al.[61] 50 7.2 PDR 50Gy/5 50 4% 56%
Arthur et al.[62] 99 7 LDR/HDR LDR = 3.5 -5 days HDR = 3.4 × 10 45 Gy (LDR) 34 Gy (HDR 4% n/a
Polgar et al.[63] 128 6.8 HDR 5.2 × 7 36.4 Gy 4.7% 77%
King et al [64] 51 6.25 LDR/HDR LDR = 4 days 4 Gyx8 45 Gy (LDR) 32 Gy (HDR) 3.9% 75%
Otto et al. [65] 274 5.25 PDR/HDR PDR 5 days, 0.6 Gy/hr HDR = 4 Gyx8 49.8 Gy (PDR) 32 Gy (HDR) 2.9% 92%
Polgar et al.[58] 45 11.1 HDR 4.33 × 7 5.2 × 7 30.3 Gy 36.4 Gy 4.4% 78%
  1. LR = local recurrence, HDR = high dose rate, LDR = low dose rate, PDR = pulsed dose rate, n/a = data not available