Table 3 The 3-year disease-free survival and locoregional control according to surgical margins
From: Buccal mucosa carcinoma: surgical margin less than 3 mm, not 5 mm, predicts locoregional recurrence
Surgical margin | Disease-free survival (%) | p | Locoregional control (%) | p |
|---|---|---|---|---|
1 mm | ||||
≤1 mm | 56 | 0.02* | 59 | <0.01* |
>1 mm | 77 | 81 | ||
HR, univariate | 0.4 (95% CI, 0.19-0.86) | 0.02 | 0.4 (95% CI, 0.16-0.80) | 0.01 |
HR, multivariate | 0.2 (95% CI, 0.06-0.72) | 0.02 | 0.2 (95% CI, 0.05-0.67) | 0.01 |
2 mm | ||||
≤2 mm | 59 | <0.01* | 64 | <0.01* |
>2 mm | 93 | 97 | ||
HR, univariate | 0.1 (95% CI, 0.03-0.62) | <0.01 | 0.1 (95% CI, 0.01-0.64) | 0.02 |
HR, multivariate | 0.1 (95% CI, 0.01-0.60) | 0.01 | 0.1 (95% CI, 0.01-0.72) | 0.02 |
3 mm | ||||
≤3 mm | 67 | 0.06* | 71 | 0.04* |
>3 mm | 91 | 95 | ||
HR, univariate | 0.3 (95% CI, 0.06-1.16) | 0.08 | 0.2 (95% CI, 0.02-1.19) | 0.07 |
HR, multivariate | 0.2 (95% CI, 0.03-1.86) | 0.17 | 0.3 (95% CI, 0.03-2.12) | 0.21 |
4 mm | ||||
≤4 mm | 69 | 0.13* | 73 | 0.09* |
>4 mm | 89 | 94 | ||
HR, univariate | 0.3 (95% CI, 0.08-1.49) | 0.15 | 0.2 (95% CI, 0.03-1.53) | 0.12 |
HR, multivariate | 0.3 (95% CI, 0.04-2.16) | 0.22 | 0.3 (95% CI, 0.04-2.52) | 0.28 |
5 mm | ||||
≤5 mm | 72 | 0.36* | 75 | 0.22* |
>5 mm | 86 | 92 | ||
HR, univariate | 0.5 (95% CI, 0.12-2.22) | 0.37 | 0.3 (95% CI, 0.04-2.30) | 0.25 |
HR, multivariate | 0.5 (95% CI, 0.07-4.22) | 0.56 | 0.6 (95% CI, 0.08-4.80) | 0.63 |